The Center is a collaboration among scientists, clinicians and patient. The Breast Research Patient Registry is a focus of the Center. Women who enroll in the Registry provide information about lifestyle factors, possible chemical exposures and health history. Most women also allow use of tissues and related clinical information. Identities of participants are protected to ensure confidentiality. Women enrolled may be offered to participate in related studies aimed to improve the management of symptoms during treatment or programs to enhance the longterm quality of life. The Center utilizes the Research Infrastructure of the Pioneer Valley Life Sciences institute to assist researchers. The Center also provides a grant program to support targeted research initiatives representing the priorities developed by the patients, clinicians and scientists on the Review Board.